Suite 303, Highland House, 165 The Broadway, Wimbledon, SW19 1NE, UK
Biodegradable Collagen Matrix
Device description
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Type I atelocollagen with a 3D porous structure and pore diameter between 10-300µm
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Comprises > 90% atelocollagen and < 10% glycosaminoglycan (GAG)
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Dry form scaffold
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Biodegraded in approximately 3 to 6 months
Surgery & Mechanism
Ologen™ Collagen Matrix helps to control scar formation.
Myofibroblasts that are involved in the remodelling phase of wound healing migrate into the ologen™ CM scaffold, settle and adhere.
While a new collagen matrix is being produced by the Myofibroblasts, the ologen™ CM starts to degrade.
ologen™ CM degradation process continues and the scaffold is replaced by myofibroblast produced matrix.
Combination of XEN + MMC and ologen™ Collagen Matrix - IOL injector technique
Schematic representation of the surgical technique
ologen™ CM present
Early bleb fibrosis (<1 month)
7.7%*
to
4.3%**
ologen™ CM present
Late bleb fibrosis (1 month - 1 year)
46%*
to
4.3%**
at 12 months
ologen™ CM present
Needling procedures
23.1%*
to
13%**
at 12 months
*n=39 (eye evaluated at 12 months) 1 **n=23 (eye evaluated at 12 months)1
References:
1. Rodríguez, José MN, et al. "Efficacy of the Ologen® collagen matrix in combination with the XEN® gel stent implantation in the treatment of openangle glaucoma: a case‐control study." Clinical & Experimental Ophthalmology (2020).
The use of ologen™ Collagen Matrix in combination with XEN implant results in a significant reduction of IOP and number of medications, as well as a better control of conjunctival fibrosis, less need for postoperative interventions with no significant added risk.
Contact Us
Suite 303, Highland House, 165 The Broadway, Wimbledon, SW19 1NE, UK
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T: +44 (0)20 8944 7585.
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General Enquiries:
[email protected] -
Sale Enquiries:
[email protected]
About Us
Welcome to ProSys International Limited. We design, manufacture and market a wide range of UKCA and CE marked Medical Devices for a multitude of clinical specialities & applications. We are the exclusive UK & Ireland distributor for one of Europe’s leading manufacturers of medical devices, Dahlhausen.
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